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BLK Antibody

Catalog Number:

35390
other_names: MGC10442 antibody; MODY11 antibody; BLK antibody; b lymphocyte kinase antibody; tyrosine-protein kinase Blk antibody; BLK nonreceptor tyrosine kinase antibody; p55-Blk antibody; B lymphoid tyrosine kinase antibody

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P51451;
NCBI Gene#:640

Form of Antibody:

Rabbit IgG in 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage/Stability:

Immunogen:

Recombinant fragment corresponding to a region within amino acids 191 and 382 of BLK.

Purification:

Antibodies were purified by antigen-affinity chromatography.

Specificity/Sensitivity:

The antibody detects endogenous levels of total BLK protein.

Applications:

WB

Background:

This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq]

References:

appl_detail:

Western blotting: 1:500-1:3000

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