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Catalog Number: |
35390 |
| other_names: | MGC10442 antibody; MODY11 antibody; BLK antibody; b lymphocyte kinase antibody; tyrosine-protein kinase Blk antibody; BLK nonreceptor tyrosine kinase antibody; p55-Blk antibody; B lymphoid tyrosine kinase antibody |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:P51451; |
Form of Antibody: |
Rabbit IgG in 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Storage/Stability: |
|
Immunogen: |
Recombinant fragment corresponding to a region within amino acids 191 and 382 of BLK. |
Purification: |
Antibodies were purified by antigen-affinity chromatography. |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total BLK protein. |
Applications: |
WB |
Background: |
This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq] |
References: |
|
appl_detail: |
Western blotting: 1:500-1:3000 |
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