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Catalog Number: |
35373 |
| other_names: | FLJ44809 antibody; FRAP antibody; FRAP1 antibody; FRAP2 antibody; RAFT1 antibody; RAPT1 antibody; MTOR antibody; FK506 binding protein 12-rapamycin associated protein 2 antibody; FK506-binding protein 12-rapamycin complex-associated protein 1 antibody; FK |
Amount: |
100μg |
| calculated_mw: | |
| host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:P42345; |
Form of Antibody: |
Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
Storage/Stability: |
|
Immunogen: |
Recombinant fragment corresponding to a region within amino acids 1287 and 1569 of mTOR. |
Purification: |
Antibodies were purified by antigen-affinity chromatography. |
Specificity/Sensitivity: |
The antibody detects endogenous levels of total mTOR protein. |
Applications: |
WB |
Background: |
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq] |
References: |
|
appl_detail: |
Western blotting: 1:500-1:3000 |
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