EIF4A2 Antibody

Catalog Number:

35372

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q14240;
NCBI Gene#:1974

Form of Antibody:

Rabbit IgG in 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage/Stability:

Immunogen:

Recombinant fragment contain a sequence corresponding to a region within amino acids 1 and 96 of EIF4A2.

Purification:

Antibodies were purified by antigen-affinity chromatography.

Specificity/Sensitivity:

The antibody detects endogenous levels of total EIF4A2 protein.

Applications:

WB

Background:

ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

References:

appl_detail:

Western blotting: 1:100-1:1000

Datasheet PDF