c-Fos Antibody

Catalog Number:

35359

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P01100;
NCBI Gene#:2353

Form of Antibody:

Rabbit IgG in 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage/Stability:

Immunogen:

Recombinant fragment contain a sequence corresponding to a region within amino acids 77 and 375 of c-Fos.

Purification:

Antibodies were purified by antigen-affinity chromatography.

Specificity/Sensitivity:

The antibody detects endogenous levels of total c-Fos protein.

Applications:

WB

Background:

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq]

References:

appl_detail:

Western blotting: 1:1000-1:10000

Datasheet PDF