VASH1 Antibody

Catalog Number:

35319

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q7L8A9
NCBI Gene ID: 22846

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human VASH1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total VASH1 protein.

Applications:

WB

Background:

Angiogenesis inhibitor. Inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. Does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis. Acts in an autocrine manner. Inhibits artery neointimal formation and macrophage infiltration. Exhibits heparin-binding activity.

Kikuno R., DNA Res. 6:197-205(1999).
Bechtel S., BMC Genomics 8:399-399(2007).
Heilig R., Nature 421:601-607(2003).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF