STK10 Antibody

Catalog Number:

35288

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O94804
NCBI Gene ID: 6793

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human STK10.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total STK10 protein.

Applications:

WB

Background:

Serine/threonine-protein kinase involved in regulation of lymphocyte migration. Phosphorylates MSN, and possibly PLK1. Involved in regulation of lymphocyte migration by mediating phosphorylation of ERM proteins such as MSN. Acts as a negative regulator of MAP3K1/MEKK1. May also act as a cell cycle regulator by acting as a polo kinase kinase: mediates phosphorylation of PLK1 in vitro; however such data require additional evidences in vivo.

Kuramochi S., Immunogenetics 49:369-375(1999).
Ota T., Nat. Genet. 36:40-45(2004).
Schmutz J., Nature 431:268-274(2004).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF