KCNJ4 Antibody

Catalog Number:

35275

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P48050
NCBI Gene ID: 3761

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human KCNJ4.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total KCNJ4 protein.

Applications:

WB

Background:

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium By similarity.

Perier F., Proc. Natl. Acad. Sci. U.S.A. 91:6240-6244(1994).
Tang W., FEBS Lett. 348:239-243(1994).
Makhina E.N., J. Biol. Chem. 269:20468-20474(1994).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF