Cytochrome P450 3A7 Antibody

Catalog Number:

35259

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: A4D288/P24462
NCBI Gene ID: 1551

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human Cytochrome P450 3A7.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Cytochrome P450 3A7 protein.

Applications:

WB

Background:

This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of related genes on chromosome 7q21.1. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3AP1 pseudogene and is represented by GeneID:100861540.

Komori M., J. Biochem. 105:161-163(1989).
Gellner K., Pharmacogenetics 11:111-121(2001).
Scherer S.W., Science 300:767-772(2003).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF