THAS Antibody

Catalog Number:

35257

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P24557
NCBI Gene ID: 6916

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from C-terminal of human THAS.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total THAS protein.

Applications:

WB

Background:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Yokoyama C., Biochem. Biophys. Res. Commun. 178:1479-1484(1991).
Ohashi K., J. Biol. Chem. 267:789-793(1992).
Miyata A., Eur. J. Biochem. 224:273-279(1994).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF