TRAF4 Antibody

Catalog Number:

35240

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9BUZ4
NCBI Gene ID: 9618

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human TRAF4.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TRAF4 protein.

Applications:

WB

Background:

Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract By similarity. Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions.

Tomasetto C.L., Genomics 28:367-376(1995).
Miller H.G., Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.
Cai C.L., Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF