LIPB1 Antibody

Catalog Number:

35188

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: C20615
NCBI Gene ID: 8496

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human LIPB1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total LIPB1 protein.

Applications:

WB

Background:

The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Serra-Pages C., J. Biol. Chem. 273:15611-15620(1998).
Nagase T., DNA Res. 6:337-345(1999).
Nakajima D., DNA Res. 9:99-106(2002).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF