LRRK2 Antibody

Catalog Number:

35803

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q5S007
NCBI Gene ID: 120892
Gene Accssion: BC117180

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to a region derived from internal residues of human leucine-rich repeat kinase 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total LRRK2 protein.

Applications:

IHC

Background:

This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF