TNFRSF10D Antibody

Catalog Number:

35312

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9UBN6
NCBI Gene ID: 8793

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human TNFRSF10D.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TNFRSF10D protein.

Applications:

WB

Background:

Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to it cannot but according to it can induce the NF-kappa-B pathway.

Marsters S.A., Curr. Biol. 7:1003-1006(1997).
Degli-Esposti M.A., Immunity 7:813-820(1997).
Pan G., FEBS Lett. 424:41-45(1998).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF