Cytochrome P450 20A1 Antibody

Catalog Number:

35271

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q6UW02
NCBI Gene ID: 57404

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human Cytochrome P450 20A1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Cytochrome P450 20A1 protein.

Applications:

WB

Background:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein lacks one amino acid of the conserved heme binding site. It also lacks the conserved I-helix motif AGX(D,E)T, suggesting that its substrate may carry its own oxygen.

Clark H.F., Genome Res. 13:2265-2270(2003).
Hillier L.W., Nature 434:724-731(2005).
Colinge J., Submitted (OCT-2008) to UniProtKB.

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF