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USP36 Antibody

Catalog Number:

35121
other_names: Ubiquitin carboxyl-terminal hydrolase 36; EC 3.1.2.15; Ubiquitin thioesterase 36; Ubiquitin-specific-processing protease 36; Deubiquitinating enzyme 36

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9P275
NCBI Gene ID: 57602

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human USP36.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total USP36 protein.

Applications:

IHC

Background:

May be required for maintaining multiple types of adult stem cells. May function as a transcriptional repressor by continually deubiquiting histone H2B at the promoters of genes critical for cellular differentiation, thereby preventing histone H3 'Lys-4' trimethylation (H3K4) By similarity.

Nagase T., DNA Res. 7:143-150(2000).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Ota T., Nat. Genet. 36:40-45(2004).

References:

appl_detail:


Immunohistochemistry: 1:50~1:100

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