MTERF Antibody

Catalog Number:

35106

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q99551
NCBI Gene ID: 7978

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human MTERF.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MTERF protein.

Applications:

WB IHC

Background:

Transcription termination factor. Binds to a 28 bp region within the tRNA(Leu(uur)) gene at a position immediately adjacent to and downstream of the 16S rRNA gene; this region comprises a tridecamer sequence critical for directing accurate termination. Binds DNA along the major grove and promotes DNA bending and partial unwinding. Promotes base flipping. Probably requires one or more components for termination activity.

Fernandez-Silva P., EMBO J. 16:1066-1079(1997).
Suzuki Y., Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Hillier L.W., Nature 424:157-164(2003).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF