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SFRS8 Antibody

Catalog Number:

35077
other_names: Splicing factor; arginine/serine-rich 8; Suppressor of white apricot protein homolog; SFRS8; SWAP

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q12872
NCBI Gene ID: 6433

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human SFRS8.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SFRS8 protein.

Applications:

WB

Background:

Plays a role as an alternative splicing regulator. Regulate its own expression at the level of RNA processing. Also regulates the splicing of fibronectin and CD45 genes. May act, at least in part, by interaction with other R/S-containing splicing factors. Represses the splicing of MAPT/Tau exon 10.

Denhez F., J. Biol. Chem. 269:16170-16179(1994).
Scherer S.E., Nature 440:346-351(2006).

References:

appl_detail:

Western blotting: 1:500~1:3000

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