SCN2B Antibody

Catalog Number:

35057

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O60939
NCBI Gene ID: 6327

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human SCN2B.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SCN2B protein.

Applications:

WB

Background:

Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier By similarity.

Eubanks J., NeuroReport 8:2775-2779(1997).
Bolino A., Eur. J. Hum. Genet. 6:629-634(1998).
Cruz J.S., Science 284:711-711(1999).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF