SCN7A Antibody

Catalog Number:	35055
other_names:	Sodium channel protein type 7 subunit alpha; Sodium channel protein type VII subunit alpha; Putative voltage-gated sodium channel subunit alpha Nax; Sodium channel protein cardiac and skeletal muscle subunit alpha; SCN7A
Amount:	100μg
calculated_mw:
host_species:	Rabbit
Price:	$319
Swiss-Prot No:	Swiss-Prot: Q01118 NCBI Gene ID: 6332
Form of Antibody:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability:
Immunogen:	Synthesized peptide derived from internal of human SCN7A.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity/Sensitivity:	The antibody detects endogenous levels of total SCN7A protein.
Applications:	IF
Background:	Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. George A.L. Jr., Proc. Natl. Acad. Sci. U.S.A. 89:4893-4897(1992).
References:
appl_detail:	Immunofluorescence: 1:100~1:500
	Datasheet PDF

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