SH2D2A Antibody

Catalog Number:

35041

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9NP31
NCBI Gene ID: 9047

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human SH2D2A.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SH2D2A protein.

Applications:

WB

Background:

Could be a T-cell-specific adapter protein involved in the control of T-cell activation. May play a role in the CD4-p56-LCK-dependent signal transduction pathway. Could also play an important role in normal and pathological angiogenesis. Could be an adapter protein that facilitates and regulates interaction of KDR with effector proteins important to endothelial cell survival and proliferation.

Spurkland A., J. Biol. Chem. 273:4539-4546(1998).
Wu L.-W., J. Biol. Chem. 275:6059-6062(2000).
Lee J.-S., Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases.

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF