PPP2R2B Antibody

Catalog Number:

35028

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q00005
NCBI Gene ID: 5521

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human PPP2R2B.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PPP2R2B protein.

Applications:

WB

Background:

The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity By similarity. Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance By similarity.

Mayer R.E., Biochemistry 30:3589-3597(1991) [PubMed: 1849734].
Ota T., Nat. Genet. 36:40-45(2004) [PubMed: 14702039].
Schmutz J., Nature 431:268-274(2004) [PubMed: 15372022].

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF