ARHGEF12 Antibody

Catalog Number:

34992

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9NZN5
NCBI Gene ID: 23365

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human ARHGEF12.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ARHGEF12 protein.

Applications:

WB

Background:

May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.

Kourlas P.J., Proc. Natl. Acad. Sci. U.S.A. 97:2145-2150(2000).
The MGC Project Team, Genome Res. 14:2121-2127(2004).
Nagase T., DNA Res. 4:141-150(1997).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF