RGS10 Antibody

Catalog Number:

34980

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O43665
NCBI Gene ID: 6001

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human RGS10.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total RGS10 protein.

Applications:

WB

Background:

Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Associates specifically with the activated forms of the G protein subunits G(i)-alpha and G(z)-alpha but fails to interact with the structurally and functionally distinct G(s)-alpha subunit. Activity on G(z)-alpha is inhibited by palmitoylation of the G-protein.

Hunt T.W., Nature 383:175-177(1996).
Chatterjee T.K., J. Biol. Chem. 275:24013-24021(2000).
Burgon P.G., J. Biol. Chem. 276:32828-32834(2001).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF