SNX3 Antibody

Catalog Number:

35070

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O60493
NCBI Gene ID: 8724

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human SNX3.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SNX3 protein.

Applications:

WB

Background:

Phosphoinositide-binding protein required for multivesicular body formation. Specifically binds phosphatidylinositol 3-phosphate (PtdIns(P3)). Plays a role in protein transport between cellular compartments. Promotes stability and cell surface expression of epithelial sodium channel (ENAC) subunits SCNN1A and SCNN1G By similarity. Not involved in EGFR degradation.

Haft C.R., Mol. Cell. Biol. 18:7278-7287(1998).
Xu Y., Nat. Cell Biol. 3:658-666(2001).
Hayama A., Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF