PC Antibody

Catalog Number:

34943

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P11498
NCBI Gene ID: 5091

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human PC.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PC protein.

Applications:

WB IHC

Background:

Pyruvate carboxylase catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. Catalyzes in a tissue specific manner, the initial reactions of glucose (liver, kidney) and lipid (adipose tissue, liver, brain) synthesis from pyruvate.

Wexler I.D., Biochim. Biophys. Acta 1227:46-52(1994).
Mackay N., Biochem. Biophys. Res. Commun. 202:1009-1014(1994).
Lamhonwah A.-M., Arch. Biochem. Biophys. 254:631-636(1987).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF