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PIK3R5 Antibody

Catalog Number:

34903
other_names: Phosphoinositide 3-kinase regulatory subunit 5; PI3-kinase regulatory subunit 5; PI3-kinase p101 subunit; PtdIns-3-kinase p101; p101-PI3K

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q8WYR1
NCBI Gene ID: 23533

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human PIK3R5.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total PIK3R5 protein.

Applications:

WB IHC IF

Background:

Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma membrane via interaction with beta-gamma G protein dimers. Required for G protein-mediated activation of PIK3CG By similarity.

The MGC Project Team;Genome Res. 14:2121-2127(2004).
Sjoeblom T.,Science 314:268-274(2006).
Suire S., Curr. Biol. 15:566-570(2005).

References:

appl_detail:


Immunohistochemistry: 1:50~1:100

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