OAT Antibody

Catalog Number:

34882

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P04181
NCBI Gene ID: 4942

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from Internal of human OAT.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total OAT protein.

Applications:

WB

Background:

This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome.

ana G., Proc. Natl. Acad. Sci. U.S.A. 83:1203-1207(1986).
Ramesh V., DNA 5:493-501(1986).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF