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MYO9B Antibody

Catalog Number:

34823
other_names: Myosin-Ixb; Unconventional myosin-9b;

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q13459
NCBI Gene ID: 4650

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from N-terminal of human MYO9B.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total MYO9B protein.

Applications:

WB

Background:

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. May be involved in the remodeling of the actin cytoskeleton. Binds actin with high affinity both in the absence and presence of ATP and its mechanochemical activity is inhibited by calcium ions. Also acts as a GTPase activating protein on Rho.

Wirth J.A., J. Cell Sci. 109:653-661(1996).
Grewal P.K., Gene 240:389-398(1999).
Post P.L., J. Cell Sci. 111:941-950(1998).

References:

appl_detail:

Western blotting: 1:500~1:3000

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