FMN2 Antibody

Catalog Number:

34687

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9NZ56
NCBI Gene ID: 56776

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human FMN2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total FMN2 protein.

Applications:

IHC

Background:

Required for asymmetric spindle positioning, asymmetric oocyte division and polar body extrusion during female germ cell meiosis By similarity. Actin-binding protein that is involved in actin cytoskeleton assembly and reorganization. Acts as an actin nucleation factor and promotes assembly of actin filaments together with SPIRE1 and SPIRE2. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Plays a role in responses to DNA damage, cellular stress and hypoxia by protecting CDKN1A against degradation, and thereby plays a role in stress-induced cell cycle arrest. Protects cells against apoptosis by protecting CDKN1A against degradation.

toki Y., Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Leader B., " Mech. Dev. 93:221-231(2000).
Matsuoka S., Science 316:1160-1166(2007).

References:

appl_detail:

Immunohistochemistry: 1:50~1:100

Datasheet PDF