RFX2 Antibody

Catalog Number:

34650

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P48378
NCBI Gene ID: 5990

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human RFX2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total RFX2 protein.

Applications:

IHC

Background:

a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites.

Reith W., Mol. Cell. Biol. 14:1230-1244(1994).
Sjoeblom T., Science 314:268-274(2006).

References:

appl_detail:

Immunohistochemistry: 1:50~1:100

Datasheet PDF