CHSY1 Antibody

Catalog Number:	34588
other_names:	carbohydrate (chondroitin) synthase 1; chondroitin glucuronyltransferase II; chondroitin synthase; CHSS1; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1
Amount:	100μg
calculated_mw:
host_species:	Rabbit
Price:	$319
Swiss-Prot No:	Swiss-Prot: Q86X52 NCBI Gene ID: 22856
Form of Antibody:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability:
Immunogen:	Synthesized peptide derived from internal of human CHSY1.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity/Sensitivity:	The antibody detects endogenous levels of total CHSY1 protein.
Applications:	WB IHC
Background:	Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling. Kitagawa H., J. Biol. Chem. 276:38721-38726(2001). Nagase T., DNA Res. 6:63-70(1999). Clark H.F., Genome Res. 13:2265-2270(2003).
References:
appl_detail:	Western blotting: 1:500~1:3000 Immunohistochemistry: 1:50~1:100
	Datasheet PDF

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