CEP290 Antibody

Catalog Number:

34563

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: O15078
NCBI Gene ID: 80184

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human CEP290.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total CEP290 protein.

Applications:

WB

Background:

Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition By similarity. Activates ATF4-mediated transcription. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes.

ayer J.A., Nat. Genet. 38:674-681(2006).
Nagase T., DNA Res. 4:141-150(1997).
Scherer S.E., Nature 440:346-351(2006).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF