LFNG Antibody

Catalog Number:

34489

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q8NES3
NCBI Gene ID: 3955

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human LFNG.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total LFNG protein.

Applications:

WB

Background:

Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Decreases the binding of JAGGED1 to NOTCH2 but not that of DELTA1. Essential mediator of somite segmentation and patterning By similarity.

Johnston S.H., Development 124:2245-2254(1997).
Cole S.E., Dev. Cell 3:75-84(2002).
Shimizu K., J. Biol. Chem. 276:25753-25758(2001)

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF