ABCA13 Antibody

Catalog Number:

34456

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q86UQ4
NCBI Gene ID: 154664

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human ABCA13.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ABCA13 protein.

Applications:

IF

Background:

In human, the ATP-binding cassette (ABC) family of transmembrane transporters has at least 48 genes and 7 gene subfamilies. This gene is a member of ABC gene subfamily A (ABCA). Genes within the ABCA family typically encode several thousand amino acids. Like other ABC transmembrane transporter proteins, this protein has 12 or more transmembrane alpha-helix domains that likely arrange to form a single central chamber with multiple substrate binding sites. It is also predicted to have two large extracellular domains and two nucleotide binding domains as is typical for ABCA proteins. Alternative splice variants have been described but their biological validity has not been demonstrated.

Prades C., Cytogenet. Genome Res. 98:160-168(2002).
Ota T., Nat. Genet. 36:40-45(2004).
Schaap F.G., Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.

References:

appl_detail:

Immunofluorescence: 1:100~1:500

Datasheet PDF