ATG16L1 Antibody

Catalog Number:

34474

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q676U5
NCBI Gene ID: 55054

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from Internal of human ATG16L1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ATG16L1 protein.

Applications:

WB

Background:

Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.

Zheng H., DNA Seq. 15:303-305(2004).
Hampe J., Nat. Genet. 39:207-211(2007).
Clark H.F., Genome Res. 13:2265-2270(2003).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF