POLDIP3 Antibody

Catalog Number:

34909

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9BY77
NCBI Gene ID: 84271

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human POLDIP3.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total POLDIP3 protein.

Applications:

WB

Background:

Is involved in regulation of translation. Is preferentially associated with CBC-bound spliced mRNA-protein complexes during the pioneer round of mRNA translation. Contributes to enhanced translational efficiency of spliced over nonspliced mRNAs. Recruits activated ribosomal protein S6 kinase beta-1 I/RPS6KB1 to newly synthesized mRNA. Involved in nuclear mRNA export; probably mediated by assoociation with the TREX complex.

Liu L., J. Biol. Chem. 278:10041-10047(2003).
Hirosawa M., DNA Res. 8:1-9(2001).
Collins J.E., Genome Res. 13:27-36(2003).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF