Cytochrome P450 2A13 Antibody

Catalog Number:

34233

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q16696
NCBI Gene ID: 1553

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human Cytochrome P450 2A13.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Cytochrome P450 2A13 protein.

Applications:

WB

Background:

Exhibits a coumarin 7-hydroxylase activity. Active in the metabolic activation of hexamethylphosphoramide, N,N-dimethylaniline, 2'-methoxyacetophenone, N-nitrosomethylphenylamine, and the tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Possesses phenacetin O-deethylation activity.

Fernandez-Salguero P., Am. J. Hum. Genet. 57:651-660(1995).
Su T., cer Res. 60:5074-5079(2000).
Cauffiez C., m. Biophys. Res. Commun. 317:662-669(2004).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF