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Collagen XVIII α1 Antibody

Catalog Number:

34216
other_names: Collagen alpha-1(XVIII) chain; Endostatin; COIA1;

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: P39060
NCBI Gene ID: 80781

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human Collagen XVIII α1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total Collagen XVIII α1 protein.

Applications:

IHC IF

Background:

COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube.Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.

Saarela J., Matrix Biol. 16:319-328(1998).
Elamaa H., Matrix Biol. 22:427-442(2003).
Hattori M, Nature 405:311-319(2000).

References:

appl_detail:


Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

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