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5-HT-4 Antibody

Catalog Number:

34153
other_names: 5-hydroxytryptamine receptor 4; 5-HT-4; Serotonin receptor 4; 5-HT4; HTR4

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q13639
NCBI Gene ID: 3360

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human 5-HT-4.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total 5-HT-4 protein.

Applications:

WB IF

Background:

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.

Blondel O., J. Neurochem. 70:2252-2261(1998).
Claeysen S., NeuroReport 8:3189-3195(1997).
Claeysen S., Mol. Pharmacol. 55:910-920(1999).

References:

appl_detail:

Western blotting: 1:500~1:3000

Immunofluorescence: 1:100~1:500

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