14-3-3 θ Antibody

Catalog Number:

34148

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: P27348
NCBI Gene ID: 10971

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human 14-3-3 θ.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total 14-3-3 θ protein.

Applications:

WB

Background:

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.

Nielsen P.J., Biochim. Biophys. Acta 1088:425-428(1991).
Leffers H., J. Mol. Biol. 231:982-998(1993).
Gevaert K., Nat. Biotechnol. 21:566-569(2003).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF