ASF1A Antibody

Catalog Number:

34126

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9Y294
NCBI Gene ID: 25842

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human ASF1A.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ASF1A protein.

Applications:

WB

Background:

Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.

Munakata T., Genes Cells 5:221-233(2000).
Sillje H.H.W., Curr. Biol. 11:1068-1073(2001).
Lai C.-H., Genome Res. 10:703-713(2000).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF