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JIP3 Antibody

Catalog Number:

34121
other_names: C-jun-amino-terminal kinase interacting protein 3; JIP-3; JIP3; JNK MAP kinase scaffold protein 3; JNK-interacting protein 3

Amount:

100μg
calculated_mw:
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9UPT6
NCBI Gene ID: 23162

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human JIP3.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total JIP3 protein.

Applications:

WB IF

Background:

The JNK-interacting protein (JIP) group of scaffold proteins selectively mediates JNK signaling by aggregating specific components of the MAPK cascade to form a functional JNK signaling module. May function as a regulator of vesicle transport, through interactions with the JNK-signaling components and motor proteins By similarity. UniProtKB Q9ESN9

Hattori A., DNA Res. 7:357-366(2000).
Martin J., Nature 432:988-994(2004).
Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).


References:

appl_detail:

Western blotting: 1:500~1:3000

Immunofluorescence: 1:100~1:500

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