GTF2IRD1 Antibody

Catalog Number:

34106

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9UHL9
NCBI Gene ID: 9569

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from N-terminal of human GTF2IRD1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total GTF2IRD1 protein.

Applications:

WB

Background:

May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8 By similarity.

Yan X., Biochem. J. 345:749-757(2000).
Hillier L.W., Nature 424:157-164(2003).
Tussie-Luna M.I., Proc. Natl. Acad. Sci. U.S.A. 98:7789-7794(2001).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF