NXF1 Antibody

Catalog Number:

34096

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9UBU9
NCBI Gene ID: 10482

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from N-terminal of human NXF1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total NXF1 protein.

Applications:

WB

Background:

Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export.

Braun I.C., EMBO J. 18:1953-1965(1999).
Kang Y., Genes Dev. 13:1126-1139(1999).
Bear J., Mol. Cell. Biol. 19:6306-6317(1999).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF