DOK5 Antibody

Catalog Number:

34089

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9P104
NCBI Gene ID: 55816

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human DOK5.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total DOK5 protein.

Applications:

WB

Background:

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.

Luo W.Q., Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.
Favre C., Genes Immun. 4:40-45(2003).
Cai D., J. Biol. Chem. 278:25323-25330(2003).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF