AZI2 Antibody

Catalog Number:

34065

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9H6S1
NCBI Gene ID: 64343

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from N-terminal of human AZI2.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total AZI2 protein.

Applications:

WB

Background:

Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1.

Fujita F., Mol. Cell. Biol. 23:7780-7793(2003).
Ota T., Nat. Genet. 36:40-45(2004).
Sasai M., J. Immunol. 174:27-30(2005).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF