ILKAP Antibody

Catalog Number:

34057

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q9H0C8
NCBI Gene ID: 80895

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human ILKAP.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ILKAP protein.

Applications:

WB IHC

Background:

Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation.

Leung-Hagesteijn C., EMBO J. 20:2160-2170(2001).
Wiemann S., Genome Res. 11:422-435(2001).
Hillier L.W., Nature 434:724-731(2005).

References:

appl_detail:

Western blotting: 1:500~1:3000
Immunohistochemistry: 1:50~1:100

Datasheet PDF