TEP1 Antibody

Catalog Number:	34040
other_names:	Telomerase-associated protein 1; Telomerase protein 1; p240; p80 telomerase homolog;
Amount:	100μg
calculated_mw:
host_species:	Rabbit
Price:	$319
Swiss-Prot No:	Swiss-Prot: Q99973 NCBI Gene ID: 7011
Form of Antibody:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage/Stability:
Immunogen:	Synthesized peptide derived from internal of human TEP1.
Purification:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity/Sensitivity:	The antibody detects endogenous levels of total TEP1 protein.
Applications:	IHC
Background:	Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC By similarity. Harrington L., Science 275:973-977(1997). Harrington L., Genes Dev. 11:3109-3115(1997). Kickhoefer V.A., J. Biol. Chem. 274:32712-32717(1999).
References:
appl_detail:	Immunohistochemistry: 1:50~1:100
	Datasheet PDF

Product Search