ANKK1 Antibody

Catalog Number:

33977

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q8NFD2
NCBI Gene ID: 255239

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human ANKK1.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total ANKK1 protein.

Applications:

WB

Background:

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP.

Neville M.J., Hum. Mutat. 23:540-545(2004).
Dubertret C., Schizophr. Res. 67:75-85(2004).
Manning G., Science 298:1912-1934(2002).

References:

appl_detail:

Western blotting: 1:500~1:3000

Datasheet PDF