DGKH Antibody

Catalog Number:

33954

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q86XP1
NCBI Gene ID: 160851

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Synthesized peptide derived from internal of human DGKH.

Purification:

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Specificity/Sensitivity:

The antibody detects endogenous levels of total DGKH protein

Applications:

IHC IF

Background:

Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). Plays a key role in promoting cell growth. Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF. Regulates the recruitment of RAF1 and BRAF from cytoplasm to membranes and their heterodimerization.

Murakami T., J. Biol. Chem. 278:34364-34372(2003) .
Dunham A., Nature 428:522-528(2004).
Ota T., Nat. Genet. 36:40-45(2004).

References:

appl_detail:

Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:500

Datasheet PDF